933 research outputs found
Fault diagnosis of pump valve spring based on improved singularity analysis
The fracture of pump valve springs is another typical fault of emulsion pump with high pressure and large discharge, which greatly influences the volumetric efficiency of emulsion pump. The fault diagnosis on pump valve springs of emulsion pump was analyzed based on the singularity analysis of continuous wavelet transform. The improved method for Lipschitz index was presented with better robustness and efficiency based on the Least Square Method. The criterion for the fracture of pump valve was confirmed. Diagnostic results indicate that it is accurate and effective of the improved method to locate the singularity of signals, identify the moment when the valve disc impacts on base or lift limiter and judge the fault diagnosis of pump valve
A Search for the Free Inner Core Nutation in VLBI Data
International audienceWe investigate the time-frequency spectrum of VLBI nutation series, including operational series released by IVS analysis centers. We focus on the interannual prograde band, where the signal as- sociated with the free inner core nutation (FICN) should be searched. We do not conclude on the detection of the FICN. However, we point out some signi cant but unexplained structures within the FICN frequency band. We also investigate whether their origin is geophysical or they are artifacts due to VLBI analysis methods or reference frame effects
The Use of Nanoscaled Fibers or Tubes to Improve Biocompatibility and Bioactivity of Biomedical Materials
Nanofibers and nanotubes have recently gained substantial interest for potential applications in tissue engineering due to their large ratio of surface area to volume and unique microstructure. It has been well proved that the mechanical property of matrix could be largely enhanced by the addition of nanoscaled fibers or tubes. At present, more and more researches have shown that the biocompatibility and bioactivity of biomedical materials could be improved by the addition of nanofibers or nanotubes. In this review, the efforts using nanofibers and nanotubes to improve biocompatibility and bioactivity of biomedical materials, including polymeric nanofibers/nanotubes, metallic nanofibers/nanotubes, and inorganic nanofibers/nanotubes, as well as their researches related, are demonstrated in sequence. Furthermore, the possible mechanism of improving biocompatibility and bioactivity of biomedical materials by nanofibers or nanotubes has been speculated to be that the specific protein absorption on the nanoscaled fibers or tubes plays important roles
HSP60, a protein downregulated by IGFBP7 in colorectal carcinoma
<p>Abstract</p> <p>Background</p> <p>In our previous study, it was well defined that <it>IGFBP7 </it>was an important tumor suppressor gene in colorectal cancer (CRC). We aimed to uncover the downstream molecules responsible for <it>IGFBP7</it>'s behaviour in this study.</p> <p>Methods</p> <p>Differentially expressed protein profiles between PcDNA3.1(<it>IGFBP7</it>)-transfected RKO cells and the empty vector transfected controls were generated by two-dimensional gel electrophoresis (2-DE) and mass spectrometry (MS) identification. The selected differentially expressed protein induced by IGFBP7 was confirmed by western blot and ELISA. The biological behaviour of the protein was explored by cell growth assay and colony formation assay.</p> <p>Results</p> <p>Six unique proteins were found differentially expressed in PcDNA3.1(<it>IGFBP7</it>)-transfected RKO cells, including albumin (ALB), 60 kDa heat shock protein(HSP60), Actin cytoplasmic 1 or 2, pyruvate kinase muscle 2(PKM2), beta subunit of phenylalanyl-tRNA synthetase(FARSB) and hypothetical protein. The downregulation of HSP60 by IGFBP7 was confirmed by western blot and ELISA. Recombinant human HSP60 protein could increase the proliferation rate and the colony formation ability of PcDNA3.1(<it>IGFBP7</it>)-RKO cells.</p> <p>Conclusion</p> <p>HSP60 was an important downstream molecule of IGFBP7. The downregulation of HSP60 induced by IGFBP7 may be, at least in part, responsible for IGFBP7's tumor suppressive biological behaviour in CRC.</p
Novel-view Synthesis and Pose Estimation for Hand-Object Interaction from Sparse Views
Hand-object interaction understanding and the barely addressed novel view
synthesis are highly desired in the immersive communication, whereas it is
challenging due to the high deformation of hand and heavy occlusions between
hand and object. In this paper, we propose a neural rendering and pose
estimation system for hand-object interaction from sparse views, which can also
enable 3D hand-object interaction editing. We share the inspiration from recent
scene understanding work that shows a scene specific model built beforehand can
significantly improve and unblock vision tasks especially when inputs are
sparse, and extend it to the dynamic hand-object interaction scenario and
propose to solve the problem in two stages. We first learn the shape and
appearance prior knowledge of hands and objects separately with the neural
representation at the offline stage. During the online stage, we design a
rendering-based joint model fitting framework to understand the dynamic
hand-object interaction with the pre-built hand and object models as well as
interaction priors, which thereby overcomes penetration and separation issues
between hand and object and also enables novel view synthesis. In order to get
stable contact during the hand-object interaction process in a sequence, we
propose a stable contact loss to make the contact region to be consistent.
Experiments demonstrate that our method outperforms the state-of-the-art
methods. Code and dataset are available in project webpage
https://iscas3dv.github.io/HO-NeRF
Demand Response Method Considering Multiple Types of Flexible Loads in Industrial Parks
With the rapid development of the energy internet, the proportion of flexible
loads in smart grid is getting much higher than before. It is highly important
to model flexible loads based on demand response. Therefore, a new demand
response method considering multiple flexible loads is proposed in this paper
to character the integrated demand response (IDR) resources. Firstly, a
physical process analytical deduction (PPAD) model is proposed to improve the
classification of flexible loads in industrial parks. Scenario generation, data
point augmentation, and smooth curves under various operating conditions are
considered to enhance the applicability of the model. Secondly, in view of the
strong volatility and poor modeling effect of Wasserstein-generative
adversarial networks (WGAN), an improved WGAN-gradient penalty (IWGAN-GP) model
is developed to get a faster convergence speed than traditional WGAN and
generate a higher quality samples. Finally, the PPAD and IWGAN-GP models are
jointly implemented to reveal the degree of correlation between flexible loads.
Meanwhile, an intelligent offline database is built to deal with the impact of
nonlinear factors in different response scenarios. Numerical examples have been
performed with the results proving that the proposed method is significantly
better than the existing technologies in reducing load modeling deviation and
improving the responsiveness of park loads.Comment: Submitted to Expert Systems with Application
学会抄録
BackgroundMany developing countries are experiencing rapid ecological changes such as deforestation and shifting agricultural practices. These environmental changes may have an important consequence on malaria due to their impact on vector survival and reproduction. Despite intensive deforestation and malaria transmission in the China-Myanmar border area, the impact of deforestation on malaria vectors in the border area is unknown.MethodsWe conducted life table studies on Anopheles minimus larvae to determine the pupation rate and development time in microcosms under deforested, banana plantation, and forested environments.ResultsThe pupation rate of An. minimus was 3.8 % in the forested environment. It was significantly increased to 12.5 % in banana plantations and to 52.5 % in the deforested area. Deforestation reduced larval-to-pupal development time by 1.9-3.3 days. Food supplementation to aquatic habitats in forested environments and banana plantations significantly increased larval survival rate to a similar level as in the deforested environment.ConclusionDeforestation enhanced the survival and development of An. minimus larvae, a major malaria vector in the China-Myanmar border area. Experimental determination of the life table parameters on mosquito larvae under a variety of environmental conditions is valuable to model malaria transmission dynamics and impact by climate and environmental changes
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